Anti-Cathepsin D (Tumor Marker) Monoclonal Antibody(Clone: CTSD/2781)
Produktgrößen
20 µg
£397,00
36-2143-20UG
100 µg
£716,00
36-2143-100UG
Über dieses Produkt
- SKU:
- 36-2143
- Zusätzliche Namen:
- CatD; Cathepsin D; Ceroid lipofuscinosis neuronal 10; CLN10; CPSD; Epididymis secretory sperm binding protein Li 130P; Lysosomal aspartyl peptidase; Lysosomal aspartyl protease
- translate.label.attr.clone:
- CTSD/2781
- Klonalität:
- Monoclonal
- Weitere Details:
- Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 43kDa preprocathepsin D that is cleaved and glycosylated to form a 46kDa procathepsin D and then further cleaved to produce 28kDa and 15kDa subunits (heavy and light chains; respectively). Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases; including breast cancer and possibly Alzheimer's disease.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment of human Cathepsin D protein (around aa 104-250) (exact sequence is proprietary)
- Isotyp:
- Mouse IgG1; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
