Anti-Catenin; beta (p120) Monoclonal Antibody(Clone: 9F2)
Produktgrößen
20 µg
£397,00
36-2137-20UG
100 µg
£716,00
36-2137-100UG
Über dieses Produkt
- SKU:
- 36-2137
- Zusätzliche Namen:
- Cadherin associated protein; beta 1 88kDa; Catenin beta-1; CATNB; CHBCAT; CTNNB1
- translate.label.attr.clone:
- 9F2
- Klonalität:
- Monoclonal
- Weitere Details:
- This MAb recognizes a protein of 92kDa; which is identified as beta-catenin. It shows no cross-reaction with gamma-catenin (also known as plakoglobin). The catenins; alpha; beta and gamma bind to the highly conserved; intracellular cytoplasmic tail of E-cadherin. Together; the catenin/cadherin complexes play an important role mediating cellular adhesion. Alpha-catenin was initially described as an E-cadherin-associated protein; and has been shown to associate with other members of the cadherin family; such as N-cadherin and P-cadherin. Beta-catenin associates with the cytoplasmic portion of E-cadherin; which is necessary for the function of E-cadherin as an adhesion molecule. Beta-catenin has also been found in complexes with the tumor suppressor protein APC.
- Host:
- Mouse
- Immunogen:
- Recombinant chicken β-catenin
- Isotyp:
- Mouse IgG1; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
