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Antikörper

Anti-CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) Monoclonal Antibody(Clone: CR2/1953)

Produktgrößen
20 µg
£397,00
36-2115-20UG
100 µg
£716,00
36-2115-100UG
Über dieses Produkt
SKU:
36-2115
Zusätzliche Namen:
CD21; Complement C3d receptor (C3DR); Complement Receptor type 2 (CR2); CVID7; EBV receptor; EBV-R; Epstein-Barr virus receptor; EVBR; SLEB9
translate.label.attr.clone:
CR2/1953
Klonalität:
Monoclonal
Weitere Details:
Recognizes a protein of 140kDa; which is identified as the complement receptor 2 (CR2) / CD21. This protein is expressed strongly on mature B cells; follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny; CD21 appears after the pre-B-stage; is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro. CD21 functions as receptor for C3d; C3dg and iC3b Complement components; for EBV and for IFNalpha. CD21 binds to CD23 and associates with CD19; CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation.
Host:
Mouse
Immunogen:
Recombinant human CR2 (CD21) protein fragment (around aa 44-196) (exact sequence is proprietary)
Isotyp:
Mouse IgG1; kappa
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody
  • Datenblatt des Herstellers:1.jpg
Fig. 2: Formalin-fixed; paraffin-embedded human Follicular Dendritic Cell Sarcoma stained with CD21 / CR2 Mouse Monoclonal Antibody (CR2/1953).
Fig. 3: SDS-PAGE Analysis Purified CD21 / CR2 Mouse Monoclonal Antibody (CR2/1953). Confirmation of Purity and Integrity of Antibody.
Fig. 4: Analysis of Protein Array containing more than 19;000 full-length human proteins using CD21 Mouse Monoclonal Antibody (CR2/1953) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array.
Fig. 4: Analysis of Protein Array containing more than 19;000 full-length human proteins using CD21 Mouse Monoclonal Antibody (CR2/1953) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array.