Anti-CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) Monoclonal Antibody(Clone: rCR2/1952)
Produktgrößen
20 µg
£397,00
36-2113-20UG
100 µg
£716,00
36-2113-100UG
Über dieses Produkt
- SKU:
- 36-2113
- Zusätzliche Namen:
- CD21; Complement C3d receptor (C3DR); Complement Receptor type 2 (CR2); CVID7; EBV receptor; EBV-R; Epstein-Barr virus receptor; EVBR; SLEB9
- translate.label.attr.clone:
- rCR2/1952
- Klonalität:
- Monoclonal
- Weitere Details:
- Recognizes a protein of 140kDa; which is identified as the complement receptor 2(CR2)/CD21. This protein is expressed strongly on mature B cells; follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny; CD21 appears after the pre-B-stage; is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro.CD21 functions as receptor for C3d; C3dg and iC3b Complement components; for EBV and for IFNalpha.CD21 binds to CD23 and associates with CD19; CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa 44-196) of human CR2 (CD21) protein (exact sequence is proprietary)
- Isotyp:
- Mouse IgG1; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
