Anti-MALT1 (MALT-Lymphoma Marker) Monoclonal Antibody (Clone: rMT1/410)
Produktgrößen
20 µg
£397,00
36-2062-20UG
100 µg
£716,00
36-2062-100UG
Über dieses Produkt
- SKU:
- 36-2062
- Zusätzliche Namen:
- Caspase-like protein; MALT lymphoma-associated translocation; MLT1; Mucosa-associated lymphoid tissue lymphoma translocation protein 1; Paracaspase
- translate.label.attr.clone:
- rMT1/410
- Klonalität:
- Monoclonal
- Weitere Details:
- Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene; which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene; which maps to human chromosome 18q21; and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10; which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells; mature B cells and plasma cells.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa701-808) of human MALT1 protein (exact sequence is proprietary)
- Isotyp:
- Mouse IgG1; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
