Mouse Monoclonal Antibody To N-Cadherin (Clone: CDH2/1573)
Produktgrößen
100 µg
£716,00
36-2002-100UG
Über dieses Produkt
- SKU:
- 36-2002
- translate.label.attr.clone:
- CDH2/1573
- Klonalität:
- Monoclonal
- Weitere Details:
- Recognizes a protein of ~140kDa; identified as N-Cadherin (NCAD); also known as CD325. N-cadherin is a 140 kDa protein belonging to a family of transmembrane molecules that mediate calcium-dependent intercellular adhesion. Cadherins are involved in controlling morphogenetic movements during development and regulate cell surface adhesion through homotypic adhesion with the same cadherin species. Expression of N-cadherin has been reported on a variety of normal tissues including neuronal; endothelial and muscle cells; and a subpopulation of early hematopoietic progenitor cells. Results aid in the classification of malignant non-carcinomatous neoplasms including mesotheliomas; chordomas; synovial sarcomas; malignant melanomas; epithelioid sarcomas; epithelioid angiosarcomas; clear cell sarcomas as well as serous and endometrioid tumors of the ovary have been demonstrated to be N-cadherin positive; whereas mucinous tumors are negative. Other N-cadherin-positive neoplasms include renal cell carcinomas and some variant breast tumors; including medullary breast carcinomas and sarcomatoid metaplastic breast carcinomas.
- Host:
- Mouse
- Immunogen:
- Recombinant human CDH2 intracellular domain was used as thye immunogen
- Isotyp:
- Mouse IgG1; kappa
- Aufreinigung:
- Affinity Chromatography
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg