Monoclonal Antibody to CD63 (Late Endosomes Marker)(Clone : SPM524)-PE
Produktgrößen
0.5 ml
£716,00
36-1959-0.5ML
Über dieses Produkt
- SKU:
- 36-1959
- Zusätzliche Namen:
- CD63||MLA1||TSPAN30
- translate.label.attr.clone:
- SPM524
- Klonalität:
- Monoclonal
- Konjugat:
- PE
- Weitere Details:
- The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets; monocytes and macrophages; and is weakly expressed on granulocytes; T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9; CD37 and CD53; which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Smooth plasma membrane fraction of MeWo cells
- Isotyp:
- Mouse IgG1; kappa
- Aufreinigung:
- Affinity Chromatography
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg