Monoclonal Antibody to CD34 (Hematopoietic Stem Cell & Endothelial Marker)(Clone : QBEnd/10)
Produktgrößen
100 µg
£716,00
36-1925-100UG
Über dieses Produkt
- SKU:
- 36-1925
- Zusätzliche Namen:
- CD34
- translate.label.attr.clone:
- QBEnd/10
- Klonalität:
- Monoclonal
- Weitere Details:
- This MAb recognizes a single chain; transmembrane; heavily glycosylated protein of 90-120kDa; which is identified as CD34. On the basis of differential sensitivity to degradation by specific enzymes; epitopes of monoclonal antibodies to CD34 are classified into three main categories; class I; class II and class III. It is a class II antibody whose epitope is resistant to neuraminidase but sensitive to glycoprotease and chymopapain. CD34 expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition; CD34 is expressed by soft tissue tumors; such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally; it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi s sarcoma; but with a lower specificity.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Detergent solubilized vesicular suspension prepared from human term placenta
- Isotyp:
- Mouse IgG1; lambda
- Aufreinigung:
- Affinity Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
