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Antikörper

Monoclonal Antibody to CD22 / BL-CAM(Clone : MYG13)

Produktgrößen
100 µg
£716,00
36-1898-100UG
Über dieses Produkt
SKU:
36-1898
Zusätzliche Namen:
CD22||SIGLEC2
translate.label.attr.clone:
MYG13
Klonalität:
Monoclonal
Weitere Details:
Recognizes a protein of 130-140kDa; identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny; CD22 is first expressed in the cytoplasm of pro-B and pre-B cells; and on the surface as B cells mature to become IgD+. It is not expressed by plasma cells; CD22 is found highly expressed in follicular mantle and marginal zone B-cells; and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.
Format:
Purified
Host:
Mouse
Immunogen:
Human Raji cells
Isotyp:
Mouse IgG1; kappa
Aufreinigung:
Affinity Chromatography
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody