Monoclonal Antibody to CD20 / MS4A1 (B-Cell Marker)(Clone : 109-3C2)
Produktgrößen
100 µg
£716,00
36-1896-100UG
Über dieses Produkt
- SKU:
- 36-1896
- Zusätzliche Namen:
- MS4A1||CD20
- translate.label.attr.clone:
- 109-3C2
- Klonalität:
- Monoclonal
- Weitere Details:
- Recognizes a protein of 30-33kDa; which is identified as CD20 (Workshop V; Code CD20.12. Workshop IV; Code B17). It recognizes an extracellular domain of CD20. It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells; being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. The protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B-cells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as calcium channel involved in B cell activation and cell cycle progression.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Stimulated human leukocytes
- Isotyp:
- Mouse IgG3; kappa
- Aufreinigung:
- Affinity Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php