Monoclonal Antibody to CD20 / MS4A1 (B-Cell Marker)(Clone : SPM494)
Produktgrößen
0.5 ml
£716,00
36-1891-0.5ML
Über dieses Produkt
- SKU:
- 36-1891
- Zusätzliche Namen:
- MS4A1||CD20
- translate.label.attr.clone:
- SPM494
- Klonalität:
- Monoclonal
- Weitere Details:
- Recognizes a protein of 30-33kDa; which is identified as CD20. Its epitope is located in the cytoplasmic domain of CD20 and was; therefore; ascribed as CD20cy in the 5th Workshop. CD20 is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells; being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. This MAb can be used for immunophenotyping of leukemia and malignant cells; B lymphocyte detection in peripheral blood and B cell localization in tissues. It reacts with the majority of B-cells present in peripheral blood and lymphoid tissues and their derived lymphomas. In lymphoid tissue; germinal center blasts and B-immunoblasts are particularly reactive. It is a reliable antibody for ascribing a B-cell phenotype in known lymphoid tissues. Rarely; CD20-positive T-cell lymphomas have been reported. Reactivity has also been noted with Reed-Sternberg cells in cases of Hodgkin s disease; particularly of lymphocyte predominant type.
- Format:
- T.C. Sup.
- Host:
- Mouse
- Immunogen:
- Human tonsil B cells
- Isotyp:
- Mouse IgG2a; kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg