Monoclonal Antibody to CD8A (Cytotoxic- & Suppressor T-Cell Marker)(Clone : C8/468)
Produktgrößen
100 µg
£716,00
36-1873-100UG
Über dieses Produkt
- SKU:
- 36-1873
- Zusätzliche Namen:
- CD8A||MAL
- translate.label.attr.clone:
- C8/468
- Klonalität:
- Monoclonal
- Weitere Details:
- CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha / beta ) or as a homodimer (CD8 alpha / alpha ). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells; CD4 and CD8 are mutually exclusive; so anti-CD8; generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes; and most peripheral T-cell lymphomas are CD4+/CD8-. Anaplastic large cell lymphoma is usually CD4+ and CD8-; and in T-lymphoblastic lymphoma/leukemia; CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Human CD8 recombinant protein
- Isotyp:
- Mouse IgG1; kappa
- Aufreinigung:
- Affinity Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg