Monoclonal Antibody to CD1b (T-Cell Surface Glycoprotein)(Clone : RIV12)
Produktgrößen
100 µg
£716,00
36-1842-100UG
Über dieses Produkt
- SKU:
- 36-1842
- Zusätzliche Namen:
- CD1B
- translate.label.attr.clone:
- RIV12
- Klonalität:
- Monoclonal
- Weitere Details:
- The mouse monoclonal antibody recognizes CD1b; a 44kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells; Langerhans cells; thymocytes; and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human; designated CD1A; 1B; 1C; 1D and 1E. CD1; a type 1 membrane protein; has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Human peripheral lymphocytes
- Isotyp:
- Mouse IgG1; kappa
- Aufreinigung:
- Affinity Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg