Monoclonal Antibody to CD1a / HTA1 (Mature Langerhans Cells Marker)(Clone : C1A/711)
Produktgrößen
100 µg
£716,00
36-1838-100UG
Über dieses Produkt
- SKU:
- 36-1838
- Zusätzliche Namen:
- CD1A
- translate.label.attr.clone:
- C1A/711
- Klonalität:
- Monoclonal
- Weitere Details:
- At least five CD1 genes (CD1a; b; c; d; and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein; expressed in association with Beta-2 microglobulin. Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X); extranodal histiocytic sarcoma; a subset of T-lymphoblastic lymphoma/leukemia; and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibodies against TTF-1 and CD5; anti-CD1a is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic lymphocytes in both typical and atypical thymomas; but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. Anti-CD1a is reported to be a new marker for perivascular epithelial cell tumor (PEComa).
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Recombinant human CD1a protein
- Isotyp:
- Mouse IgG1; kappa
- Aufreinigung:
- Affinity Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php
