Monoclonal Antibody to Cyclin D1 (G1-Cyclin & Mantle Cell Marker)(Clone : CCND1/809)
Produktgrößen
100 µg
£716,00
36-1637-100UG
Über dieses Produkt
- SKU:
- 36-1637
- Zusätzliche Namen:
- CCND1||BCL1||PRAD1
- translate.label.attr.clone:
- CCND1/809
- Klonalität:
- Monoclonal
- Weitere Details:
- Recognizes a protein of 36kDa; identified as cyclin D1. Cyclin D1; one of the key cell cycle regulators; is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). Occasionally; hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Recombinant human CCND1 protein
- Isotyp:
- Mouse IgG2a; kappa
- Aufreinigung:
- Affinity Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
