Monoclonal Antibody to Cyclin D1 (G1-Cyclin & Mantle Cell Marker)(Clone : DCS-6)-PE
Produktgrößen
0.5 ml
£716,00
36-1634-0.5ML
Über dieses Produkt
- SKU:
- 36-1634
- Zusätzliche Namen:
- CCND1||BCL1||PRAD1
- translate.label.attr.clone:
- DCS-6
- Klonalität:
- Monoclonal
- Konjugat:
- PE
- Weitere Details:
- Recognizes a protein of 36kDa; identified as cyclin D1. Cyclin D1; one of the key cell cycle regulators; is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). Occasionally; hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Human recombinant full length cyclin D1 protein
- Isotyp:
- Mouse IgG2a; kappa
- Aufreinigung:
- Affinity Chromatography
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
