Monoclonal Antibody to CD45RA (Leucocyte Marker)(Clone : SPM568)
Produktgrößen
100 µg
£716,00
36-1614-100UG
Über dieses Produkt
- SKU:
- 36-1614
- Zusätzliche Namen:
- PTPRC||CD45
- translate.label.attr.clone:
- SPM568
- Klonalität:
- Monoclonal
- Weitere Details:
- Recognizes a protein of 205kDa-220kDa; identified as CD45RA. CD45RA is isoforms of the human leukocyte common antigen (CD45). Human CD45 contains three exons which encode peptide segments designated A; B and C; respectively. The differential splicing of the exons generates at least five isoforms; ABC; AB; BC; B and O. This antibody reacts with ABC and BC isoforms. CD45RA is expressed on 40-50% of peripheral CD4+ T-cells; 50% of peripheral CD8+ T-cells; B-cells; and leukemic B-cell lines. T-cells expressing CD45RA are naive or virgin T-cells. T-cells expressing CD45RO are memory T-cells. CD45RA and CD45RO define complementary; predominantly non-overlapping populations of resting peripheral T-cells. This MAb is useful in study on the subpopulation of CD4+ or CD8+ T-cells. It can especially be used to differentiate T-cell lymphomas (CD45RO +ve) from B cell lymphomas (CD45RA +ve).
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Stimulated human leukocytes
- Isotyp:
- Mouse IgG2a; kappa
- Aufreinigung:
- Affinity Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg