Monoclonal Antibody to Beta-2 Microglobulin (Renal Failure & Tumor Marker)(Clone : B2M/961)
Produktgrößen
100 µg
£716,00
36-1593-100UG
Über dieses Produkt
- SKU:
- 36-1593
- Zusätzliche Namen:
- B2M||CDABP0092||HDCMA22P
- translate.label.attr.clone:
- B2M/961
- Klonalität:
- Monoclonal
- Weitere Details:
- Recognizes a protein of 12kDa; identified as β-2 microglobulin. Major histocompatibility complex (MHC) class 1 molecules bind to antigens for presentation on the surface of cells. The proteasome is responsible for producing these antigens from the components of foreign pathogens. MHC class 1 molecules consist of an α heavy chain that contains three subdomains (α1; α2; α3) and a non-covalent associating light chain; known as β-2-Microglobulin. β-2-Microglobulin associates with the α3 subdomain of the α heavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. The α1 and α2 domains of the α heavy chain form the peptide antigen-binding cleft. Mutations in the β-2-Microglobulin gene can enhance the progression of malignant melanoma phenotypes.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Full length recombinant human B2M protein
- Isotyp:
- Mouse IgG2b; kappa
- Aufreinigung:
- Affinity Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
