Monoclonal Antibody to NGF-Receptor (p75) / CD271 (Soft Tissue Tumor Marker)(Clone : SPM299)
Produktgrößen
100 µg
£716,00
36-1516-100UG
Über dieses Produkt
- SKU:
- 36-1516
- Zusätzliche Namen:
- NGFR||TNFRSF16
- translate.label.attr.clone:
- SPM299
- Klonalität:
- Monoclonal
- Weitere Details:
- It recognizes a glycoprotein of 75kDa; identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). Its epitope spans in aa 1-160 of extracellular domain of NGFR/NTR. NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region; a single transmembrane domain; and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development; differentiation; and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors; the high affinity p140 and low affinity p75.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- NGFR from A875 melanoma cells
- Isotyp:
- Mouse IgG1; kappa
- Aufreinigung:
- Affinity Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg