Monoclonal Antibody to Nucleolin (Marker of Human Cells)(Clone : SPM614)(Clone : SPM614)
Produktgrößen
100 µg
£716,00
36-1504-100UG
Über dieses Produkt
- SKU:
- 36-1504
- Zusätzliche Namen:
- NCL
- translate.label.attr.clone:
- SPM614
- Klonalität:
- Monoclonal
- Weitere Details:
- Recognizes a protein of ~76kDa; which is identified as Nucleolin (NCL). It is the major nucleolar phosphoprotein of growing eukaryotic cells. NCL is located mainly in dense fibrillar regions of the nucleolus. It is found associated with intranucleolar chromatin and pre-ribosomal particles. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. This MAb can be used to stain the nucleoli in cell or tissue preparations and can be used as a marker of the nucleoli in subcellular fractions. It produces a speckled pattern in the nuclei of cells of normal and malignant cells and may be used to stain the nucleoli of cells in fixed or frozen tissue sections. It can be used with paraformaldehyde fixed frozen tissue or cell preparations and formalin fixed; paraffin-embedded tissue sections.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Recombinant human NCL protein
- Isotyp:
- Mouse IgG1; kappa
- Aufreinigung:
- Affinity Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg