Monoclonal Antibody to Myogenin (Skeletal Muscle Marker)(Clone : SPM144)
Produktgrößen
100 µg
£716,00
36-1494-100UG
Über dieses Produkt
- SKU:
- 36-1494
- Zusätzliche Namen:
- MYOG||BHLHC3||MYF4
- translate.label.attr.clone:
- SPM144
- Klonalität:
- Monoclonal
- Weitere Details:
- Myogenin is a member of the MyoD family of myogenic basic helix-loop-helix (bHLH) transcription factors that also includes MyoD; Myf-5; and MRF4 (also known as herculinor Myf-6). MyoD family members are expressed exclusively in skeletal muscle and play a key role in activating myogenesis by binding to enhancer sequences of muscle-specific genes. The regulatory domain of MyoD is approximately 70 amino acids in length and includes both a basic DNA binding motif and a bHLH dimerization motif. MyoD family members share about 80% amino acid homology in their bHLH motifs. Anti-myogenin labels the nuclei of myoblasts in developing muscle tissue; and is expressed in tumor cell nuclei of rhabdomyosarcoma and some leiomyosarcomas. Positive nuclear staining may occur in Wilms tumor.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Human myogenin recombinant protein
- Isotyp:
- Mouse IgG1; kappa
- Aufreinigung:
- Affinity Chromatography
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg