Monoclonal Antibody to MUC1 / EMA / CD227 (Epithelial Marker)(Clone : SPM533)
Produktgrößen
100 µg
£716,00
36-1450-100UG
Über dieses Produkt
- SKU:
- 36-1450
- Zusätzliche Namen:
- MUC1||PUM
- translate.label.attr.clone:
- SPM533
- Klonalität:
- Monoclonal
- Weitere Details:
- In Western blotting; it recognizes proteins in MW range of 265-400kDa; identified as different glycoforms of EMA. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit and the C-terminal beta subunit. . The alpha subunit has cell adhesive properties. It can act both as an adhesion and an anti-adhesion protein. EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain; which is involved in cell signaling; through phosphorylations and protein-protein interactions. In immunohistochemical assays; it superbly stains routine formalin/paraffin carcinomas. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Delipidated extract of human milk fat globule membranes
- Isotyp:
- Mouse IgG2a; lambda
- Aufreinigung:
- Affinity Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg