Monoclonal Antibody to MAGE-1 (Target for Cancer Immunotherapy)(Clone : SPM282)
Produktgrößen
100 µg
£716,00
36-1413-100UG
Über dieses Produkt
- SKU:
- 36-1413
- Zusätzliche Namen:
- MAGEA1||MAGE1||MAGE1A
- translate.label.attr.clone:
- SPM282
- Klonalität:
- Monoclonal
- Weitere Details:
- Recognizes a protein of 42-46kDa; identified as MAGE-1. This MAb does not cross-react with MAGE-2; -3; -4; -6 -9; -10; -or -12 protein. Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous; tumor directed and specific; cytolytic; CD8+ T lymphocyte clones (CTL). The MAGE family of genes codes an important group of antigens. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma; brain tumors of glial origin; neuroblastoma; non-small cell lung cancer; breast; gastric; colorectal; ovarian; renal cell carcinomas) and not on normal tissues; the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Human MAGE-A1 full length recombinant protein
- Isotyp:
- Mouse IgG1; kappa
- Aufreinigung:
- Affinity Chromatography
- Reaktivitäten:
- Human, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg