Monoclonal Antibody to Cytokeratin 17 (KRT17) (Basal Epithelial Marker)(Clone : E3; same as Ks17.E3)
Produktgrößen
100 µg
£716,00
36-1370-100UG
Über dieses Produkt
- SKU:
- 36-1370
- Zusätzliche Namen:
- KRT17
- translate.label.attr.clone:
- E3; same as Ks17.E3
- Klonalität:
- Monoclonal
- Weitere Details:
- Cytokeratin 17 (CK17) is normally expressed in the basal cells of complex epithelia but not in stratified or simple epithelia. Antibody to CK17 is an excellent tool to distinguish myoepithelial cells from luminal epithelium of various glands such as mammary; sweat and salivary. CK17 is expressed in epithelial cells of various origins; such as bronchial epithelial cells and skin appendages. It may be considered as epithelial stem cell marker because CK17 Ab marks basal cell differentiation. CK17 is expressed in SCLC much higher than in LADC. Eighty-five percent of the triple negative breast carcinomas immunoreact with basal cytokeratins including anti-CK17. Also important is that cases of triple negative breast carcinoma with expression of CK17 show an aggressive clinical course. The histologic differentiation of ampullary cancer; intestinal vs. pancreatobiliary; is very important for treatment. Usually anti-CK17 and anti-MUC1 immunoreactivity represents pancreatobiliary subtype whereas anti-MUC2 and anti-CDX-2 positivity defines intestinal subtype.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- The cytoskeletal fraction of Rat colon epithelium
- Isotyp:
- Mouse IgG2b; kappa
- Aufreinigung:
- Affinity Chromatography
- Reaktivitäten:
- Human, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
