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Antikörper

Monoclonal Antibody to Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker)(Clone : LH2)

Produktgrößen
100 µg
£716,00
36-1363-100UG
Über dieses Produkt
SKU:
36-1363
Zusätzliche Namen:
KRT10||KPP
translate.label.attr.clone:
LH2
Klonalität:
Monoclonal
Weitere Details:
This MAb recognizes a protein of 56.5kDa; identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis; expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer; appears in the first suprabasal layers and increases in concentration towards the granular layer. However; CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm; clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm; clinical stages II and III); CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes; being preferentially detected in more-differentiated parts.
Format:
Purified
Host:
Mouse
Immunogen:
Skin extract of a human Psoriasis patient
Isotyp:
Mouse IgG1; kappa
Aufreinigung:
Affinity Chromatography
Reaktivitäten:
Human, Mouse
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody
  • Datenblatt des Herstellers:1.jpg