Monoclonal Antibody to Androgen Receptor (Marker of Androgen Dependence)(Clone : AR441)
Produktgrößen
100 µg
£716,00
36-1316-100UG
Über dieses Produkt
- SKU:
- 36-1316
- Zusätzliche Namen:
- AR||DHTR||NR3C4
- translate.label.attr.clone:
- AR441
- Klonalität:
- Monoclonal
- Weitere Details:
- Recognizes a protein of 110kDa; which is identified as androgen receptor (AR). It reacts with full length; and the newly described A form of the receptor. It does not cross react with estrogen; progesterone; or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer; AR has been proposed; as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin. This MAb is superb for staining of formalin/paraffin tissues.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- A synthetic peptide; aa 299-315; (STEDTAEYSPFKGGYTK) of human AR
- Isotyp:
- Mouse IgG1; kappa
- Aufreinigung:
- Affinity Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg