Monoclonal Antibody to HLA-DP/-DR (MHC II)(Clone : Bra-14)
Produktgrößen
100 µg
£716,00
36-1226-100UG
Über dieses Produkt
- SKU:
- 36-1226
- Zusätzliche Namen:
- DP(W3); DP(W4); HLA-SB alpha chain; MHC class II DP3-alpha; MHC class II DPA1; HLA-DP1A; HLASB
- translate.label.attr.clone:
- Bra-14
- Klonalität:
- Monoclonal
- Weitere Details:
- Reacts with a common epitope of human major histocompatibility (MHC) class II antigens; HLA-DR and DP. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36kDa) and a chain (27kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes; monocytes; macrophages; and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci; DR; DQ and DP; encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They; therefore; have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Human REH cells
- Isotyp:
- Mouse IgG3; kappa
- Aufreinigung:
- Affinity Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg