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Antikörper

Monoclonal Antibody to Cytokeratin; pan (Epithelial Marker)(Clone : AE-1/AE-3)

Produktgrößen
100 µg
£841,00
36-11121-100UG
Über dieses Produkt
SKU:
36-11121
Zusätzliche Namen:
KRT77||KRT1B
translate.label.attr.clone:
AE-1/AE-3
Klonalität:
Monoclonal
Weitere Details:
Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins; which 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8); 56.5kDa (CK10); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 40kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE-1/AE-3 is a broad spectrum anti pan-cytokeratin antibody cocktail; which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung; liver carcinoma; breast cancer; and esophageal cancer. It has been used to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas.
Format:
Purified
Host:
Mouse
Immunogen:
Human epidermal keratin
Isotyp:
Mouse IgG1 / Kappa
Aufreinigung:
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store the antibody at -20 to -80[o]C. Antibody is stable for 24 months. Nonhazardous. No MSDS required.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody