Monoclonal Antibody to MALT1 (MALT-Lymphoma Marker)(Clone : MT1/410)
Produktgrößen
100 µg
£716,00
36-1043-100UG
Über dieses Produkt
- SKU:
- 36-1043
- Zusätzliche Namen:
- MALT1||MLT
- translate.label.attr.clone:
- MT1/410
- Klonalität:
- Monoclonal
- Weitere Details:
- Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene; which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene; which maps to human chromosome 18q21; and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10; which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells; mature B cells and plasma cells.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Human MALT1 recombinant fragment (aa701-808)
- Isotyp:
- Mouse IgG1; kappa
- Aufreinigung:
- Affinity Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
