Polyclonal Antibody to HIF2A
Produktgrößen
50 µl
£511,00
35-1858-50UL
100 µl
£581,00
35-1858-100UL
Über dieses Produkt
- SKU:
- 35-1858
- Zusätzliche Namen:
- HLF|| MOP2|| ECYT4|| HIF2A|| PASD2
- Klonalität:
- Polyclonal
- Weitere Details:
- Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation seems to require recruitment of transcriptional coactivators such as CREBPB and probably EP300. Interaction with redox regulatory protein APEX seems to activate CTAD.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.547-551(P-E-E-R-L) derived from HumanHIF2A.
- Isotyp:
- Rabbit IgG
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:1.jpg