Polyclonal Antibody to HDAC3
Produktgrößen
50 µl
£511,00
35-1828-50UL
100 µl
£581,00
35-1828-100UL
Über dieses Produkt
- SKU:
- 35-1828
- Zusätzliche Namen:
- HD3|| RPD3|| RPD3-2
- Klonalität:
- Polyclonal
- Weitere Details:
- Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A; H2B; H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation; cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Probably participates in the regulation of transcription through its binding to the zinc-finger transcription factor YY1; increases YY1 repression activity. Required to repress transcription of the POU1F1 transcription factor. Acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation Wei L.-N.; Hu X.; Chandra D.; Seto E.; Farooqui M.J. Biol.Chem. 275:40782-40787(2000) Li H.; Leo C.; Zhu J.; Wu X.; O'Neil J.; Park E.-J.; Chen J.D.Mol. Cell. Biol. 20:1784-1796(2000)
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.420~424(N-D-K-E-S) derived from Human HDAC3.
- Isotyp:
- Rabbit IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:1.jpg