Polyclonal Antibody to E2F-1
Produktgrößen
50 µl
£511,00
35-1814-50UL
100 µl
£581,00
35-1814-100UL
Über dieses Produkt
- SKU:
- 35-1814
- Zusätzliche Namen:
- RBP3|| E2F-1|| RBAP1|| RBBP3
- Klonalität:
- Polyclonal
- Weitere Details:
- Transcription activator that binds DNA cooperatively with dp proteins through the E2 recognition site; 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F-1 binds preferentially RB1 protein; in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent apoptosis. P53 and E2F-1 cooperate to mediate apoptosis." Wu X.; Levine A.J. Proc. Natl. Acad. Sci. U.S.A. 91:3602-3606(1994) "Regulation of E2F1 activity by acetylation." Martinez-Balbas M.A.; Bauer U.M.; Nielsen S.J.; Brehm A.; Kouzarides T. EMBO J. 19:662-671(2000) "Regulation of E2F1 function by the nuclear corepressor KAP1." Wang C.; Rauscher F.J. III; Cress W.D.; Chen J. J. Biol. Chem. 282:29902-29909(2007)"
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.430~434(G-D-L-T-P) derived from Human E2F-1
- Isotyp:
- Rabbit IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:1.jpg