Polyclonal Antibody to MBP (myelin basic protein)
Produktgrößen
50 µl
£511,00
35-1808-50UL
100 µl
£581,00
35-1808-100UL
Über dieses Produkt
- SKU:
- 35-1808
- Zusätzliche Namen:
- MGC99675
- Klonalität:
- Polyclonal
- Weitere Details:
- The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination; maybe as components of transcriptional complexes; and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers; with each of them potentially having a specialized function. Induces T-cell proliferation.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.291~295(G-G-R-D-S
- Isotyp:
- Rabbit IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:1.jpg