Polyclonal Antibody to ATR (Ab-428)
Produktgrößen
50 µl
£511,00
35-1723-50UL
100 µl
£581,00
35-1723-100UL
Über dieses Produkt
- SKU:
- 35-1723
- Zusätzliche Namen:
- FRP1|| MEC1|| SCKL|| SCKL1
- Klonalität:
- Polyclonal
- Weitere Details:
- ATR encoded by this gene belongs the PI3/PI4-kinase family; and is most closely related to ATM; a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3; a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1; checkpoint proteins RAD17; and RAD9; as well as tumor suppressor protein BRCA1. Mutations of this gene are associated with Seckel syndrome. An alternatively spliced transcript variant of this gene has been reported; however; its full length nature is not known. Transcript variants utilizing alternative polyA sites exist.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.426~430 (G-I-S-P-K) derived from Human ATR.
- Isotyp:
- Rabbit IgG
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:1.jpg