Polyclonal Antibody to MAP2K4
Produktgrößen
50 µl
£511,00
35-1690-50UL
100 µl
£581,00
35-1690-100UL
Über dieses Produkt
- SKU:
- 35-1690
- Zusätzliche Namen:
- JNKK1|| MEK4|| MKK4|| PRKMK4|| SERK1
- Klonalität:
- Polyclonal
- Weitere Details:
- SAPK/Erk kinase (SEK1); also known as MKK4 or Jun kinase kinase (JNKK); activates the MAP kinase homologues SAPK and JNK in response to various cellular stresses and inflamatory cytokines (1-3). Activation of SEK1 occurs through MEKK phosphorylation of serine and threonine residues at positions 257 and 261; respectively. Like MEK; SEK is a dual-specificity protein kinase that phosphorylates SAPK/JNK at a conserved T*PY* site in its activation loop (4). Phosphorylation by Akt at Ser80 inhibits SEK1 and suppresses stress-activated signal transduction (5).
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.352~356(E-S-K-R-P)derived from Human MAP2K4.
- Isotyp:
- Rabbit IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:1.jpg