Polyclonal Antibody to EWS
Produktgrößen
50 µl
£511,00
35-1684-50UL
100 µl
£581,00
35-1684-100UL
Über dieses Produkt
- SKU:
- 35-1684
- Zusätzliche Namen:
- bK984G1.4|| EWSR1
- Klonalität:
- Polyclonal
- Weitere Details:
- This gene encodes a multifunctional protein that is involved in various cellular processes; including gene expression; cell signaling; and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene; specifically a t(11;22)(q24;q12) translocation; are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.213~217(T-Y-G-Q-P)derived from Human EWS.
- Isotyp:
- Rabbit IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:1.jpg