Polyclonal Antibody to TFE3
Produktgrößen
50 µl
£511,00
35-1683-50UL
100 µl
£581,00
35-1683-100UL
Über dieses Produkt
- SKU:
- 35-1683
- Zusätzliche Namen:
- BHLHE33|| TFEA|| RCCP2
- Klonalität:
- Polyclonal
- Weitere Details:
- Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB; activates the expression of CD40L in T-cells; thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box; a subset of E-boxes; present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site. Clark J.; Lu Y.-J.; Sidhar S.K.; Parker C.; Gill S. Oncogene 15:2233-2239(1997) Weterman M.A.J.; Wilbrink M.; Proc. Natl. Acad. Sci. U.S.A. 93:15294-15298(1996)
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.303~307 (L-D-V-Y-S) derived from Human TFE3.
- Isotyp:
- Rabbit IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:1.jpg