Polyclonal Antibody to CREB (Ab-129)
Produktgrößen
50 µl
£511,00
35-1598-50UL
100 µl
£581,00
35-1598-100UL
Über dieses Produkt
- SKU:
- 35-1598
- Zusätzliche Namen:
- CREB-1|| CREB1
- Klonalität:
- Polyclonal
- Weitere Details:
- CREB1 is a transcription factor that is a member of the bZIP family of DNA binding proteins. It binds as a homodimer to the CRE (cAMP-Responsive Element); an octameric palindrome containing a conserved core sequence; 5-prime-TGACG-3-prime. It consists of two transcript variants encoding respective isoforms produced by alternate splicing. It is mapped to 2q32.3-q34 . It is phosphorylated by several protein kinases and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. CREB1 is crucial for the consolidation of long-term conditioned fear memories; but not for encoding; storage; or retrieval of these memories. It is required for the stability of reactivated or retrieved conditioned fear memories .
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.127~131 (I-L-S-R-R) derived from Human CREB.
- Isotyp:
- Rabbit IgG
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:1.jpg
