Polyclonal Antibody to Merlin (Ab-518)
Produktgrößen
50 µl
£511,00
35-1591-50UL
100 µl
£581,00
35-1591-100UL
Über dieses Produkt
- SKU:
- 35-1591
- Zusätzliche Namen:
- MERL|| NF2|| Neurofibromin 2|| SCH|| Schwannomerlin
- Klonalität:
- Polyclonal
- Weitere Details:
- Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway; a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.516~520 (R-L-S-M-E) derived from Human Merlin.
- Isotyp:
- Rabbit IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:1.jpg
