Polyclonal Antibody to VASP (Ab-157)
Produktgrößen
50 µl
£511,00
35-1545-50UL
100 µl
£581,00
35-1545-100UL
Über dieses Produkt
- SKU:
- 35-1545
- Zusätzliche Namen:
- VASP
- Klonalität:
- Polyclonal
- Weitere Details:
- Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein; family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. Zhao WM; et al. (2001) EMBO J 20(9): 2315-2325. Millard TH; et al. (2005) EMBO J 24(2): 240-250. K
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.155~159 (R-V-S-N-A) derived from Human VASP.
- Isotyp:
- Rabbit IgG
- Reaktivitäten:
- Human, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:1.jpg
