Polyclonal Antibody to Myc (Ab-358)
Produktgrößen
50 µl
£511,00
35-1392-50UL
100 µl
£581,00
35-1392-100UL
Über dieses Produkt
- SKU:
- 35-1392
- Zusätzliche Namen:
- c-myc
- Klonalität:
- Polyclonal
- Weitere Details:
- Myc proto-oncogene encodes nuclear DNA-binding phosphoproteins that are involved in the regulation of gene expression and DNA replication during cell growth and differentiation. Myc encodes a protein of 65 kDa which is expressed in almost all normal and transformed cells. The expression correlates with the proliferation state of the cells. Transcription is repressed in quiescent or terminally differentiated cells. Expression of Myc is generally induced after mitogenic stimulation of cells or serum induction. Myc therefore is an important positive regulator of cell growth and proliferation. Myc has been demonstrated also to be a potent inducer of apoptosis when expressed in the absence of serum or growth factors. Apoptosis may serve also as a protective mechanism to prevent tumorigenicity elicited by deregulated Myc expression. Sequences of the Myc oncogene have been highly conserved throughout evolution; from Drosophila to vertebrates
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.356~360 (R-R-T-H-N) derived from Human Myc.
- Isotyp:
- Rabbit IgG
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:1.jpg
