Polyclonal Antibody to Aurora A (phospho-Thr288)
Produktgrößen
50 µl
£511,00
35-1313-50UL
100 µl
£581,00
35-1313-100UL
Über dieses Produkt
- SKU:
- 35-1313
- Zusätzliche Namen:
- AIK|| ARK1|| AURA|| BTAK|| STK6
- Klonalität:
- Polyclonal
- Weitere Details:
- Contributes to the regulation of cell cycle progression. Required for normal mitosis. Associates with the centrosome and the spindle microtubules during mitosis and functions in centrosome maturation; spindle assembly; maintenance of spindle bipolarity; centrosome separation and mitotic checkpoint control. Phosphorylates numerous target proteins; including ARHGEF2; BRCA1; KIF2A; NDEL1; PARD3; PLK1 and BORA. Regulates KIF2A tubulin depolymerase activity By similarity. Required for normal axon formation. Plays a role in microtubule remodeling during neurite extension. Important for microtubule formation and/or stabilization. Bischoff; J.R. et al. (1998) EMBO J 17; 3052-65. Hauf; S. et al. (2003) J Cell Biol 161; 281-94. Walter; A.O. et al. (2000) Oncogene 19; 4906-16. Zhou; H. et al. (1998) Nat Genet 20; 189-93.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around phosphorylation site of threonine 288 (R-T-T(p)-L-M) derived from Human Aurora A.
- Isotyp:
- Rabbit IgG
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:1.jpg
