Polyclonal Antibody to eIF2 Alpha (phospho-Ser49)
Produktgrößen
50 µl
£511,00
35-1308-50UL
100 µl
£581,00
35-1308-100UL
Über dieses Produkt
- SKU:
- 35-1308
- Zusätzliche Namen:
- Eukaryotic translation initiation factor 2 subunit alpha
- Klonalität:
- Polyclonal
- Weitere Details:
- Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit; followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation; the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B. Kimball; S.R. (1999) Int. J. Biochem. Cell Biol. 31; 25-29. De Haro; C. et al. (1996) FASEB J. 10; 1378-1387. Sheikh; M.S. and Fornace Jr.; A.J. (1999) Oncogene 18; 6121-6128. Cheshire; J.L. et al. (1999) J. Biol. Chem. 274; 4801-4806.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around phosphorylation site of Serine 49 (L-L-S(p)-E-L) derived from Human eIF2a.
- Isotyp:
- Rabbit IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:1.jpg
