Polyclonal Antibody to NF-KB-p105/p50 (Phospho-Ser927)
Produktgrößen
50 µl
£511,00
35-1281-50UL
100 µl
£581,00
35-1281-100UL
Über dieses Produkt
- SKU:
- 35-1281
- Zusätzliche Namen:
- DNA-binding factor KBF1|| EBP-1|| NF-kappa-B1 p84/NF-kappa-B1 p98|| NF-KB1|| NF-KB-p50
- Klonalität:
- Polyclonal
- Weitere Details:
- NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation; immunity; differentiation; cell growth; tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65; RELB; NF-KB1/p105; NF-KB1/p50; REL and NF-KB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors; respectively. Hou S; et al. (2003) J Biol Chem. 278(46): 45994-45998. Baeuerle P A; et al. (1994) Annu Rev Immunol. 12:141-179. Baeuerle P A; et al. (1996) Cell 87:13-20. Haskill S; et al. (1991) Cell 65:1281-1289.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around phosphorylation site of serine 927 (C-D-S(p)-G-V) derived from Human NF-KB-p105.
- Isotyp:
- Rabbit IgG
- Reaktivitäten:
- Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:1.jpg
