Polyclonal Antibody to GSK3 Alpha/beta(Phospho-Tyr279/216)
Produktgrößen
50 µl
£511,00
35-1272-50UL
100 µl
£581,00
35-1272-100UL
Über dieses Produkt
- SKU:
- 35-1272
- Zusätzliche Namen:
- Factor A|| GSK-3 alpha/beta|| kinase GSK3-alpha/beta
- Klonalität:
- Polyclonal
- Weitere Details:
- Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase; MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain; thereby reducing its affinity for DNA. Phosphorylates MUC1 in breast cancer cells; and decreases the interaction of MUC1 with CTNNB1/beta-catenin. Phosphorylates CTNNB1/beta-catenin. Chin PC; et al. Brain Res Mol Brain Res 2005 Jun 13; 137(1-2): 193-201 Takahashi-Yanaga F; et al. Biochem Biophys Res Commun 2004 Apr 02; 316(2): 411-415 Fan G; et al. J Biol Chem 2003 Dec 26; 278(52): 52432-52436 Liao X; et al. Mol Cancer Ther 2003 Nov; 2(11): 1215-1222
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around phosphorylation site of tyrosine 279/216 (V-S-Y(p)-I-C) derived from Human GSK3 alpha/beta.
- Isotyp:
- Rabbit IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:1.jpg
