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Antikörper

Polyclonal Antibody to P38 MAPK (Phospho-Tyr182)

Produktgrößen
50 µl
£511,00
35-1234-50UL
100 µl
£581,00
35-1234-100UL
Über dieses Produkt
SKU:
35-1234
Zusätzliche Namen:
MAPK2|| MAPKAPK-2|| MAPKAPK2
Klonalität:
Polyclonal
Weitere Details:
Responds to activation by environmental stress; pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors; such as ELK1 and ATF2 and several downstream kinases; such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines; for example IL-6. May play a role in stabilization of EPO mRNA during hypoxic stress. Isoform Mxi2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform Exip may play a role in the early onset of apoptosis. Ming Zheng; et al.(2005) The FASEB Journal. 19: 109-111 Bernt van den et al.(2001) Blink Immunology; 166: 582-587 Arshad Rahman; et al. (2004) Am J Physiol Lung Cell Mol Physiol 287: L1017-L1024 Osamu Yoshino; et al. (2003) Endocrinology & Metabolism Vol. 88: 2236-2241
Format:
Purified
Host:
Rabbit
Immunogen:
Peptide sequence around phosphorylation site of tyrosine 182 (T-G-Y(p)-V-A) derived from Human P38 MAPK.
Isotyp:
Rabbit IgG
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
Hersteller:
Abeomics
Typ:
Antibodies:Polyclonal Antibody
  • Datenblatt des Herstellers:1.jpg