Polyclonal Antibody to P38 MAPK (Phospho-Thr180)
Produktgrößen
50 µl
£511,00
35-1233-50UL
100 µl
£581,00
35-1233-100UL
Über dieses Produkt
- SKU:
- 35-1233
- Zusätzliche Namen:
- MAPK2|| MAPKAPK-2|| MAPKAPK2
- Klonalität:
- Polyclonal
- Weitere Details:
- Responds to activation by environmental stress; pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors; such as ELK1 and ATF2 and several downstream kinases; such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines; for example IL-6. May play a role in stabilization of EPO mRNA during hypoxic stress. Isoform Mxi2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform Exip may play a role in the early onset of apoptosis. Kim JE; et al. (2005) J Proteome Res Jul-Aug; 4(4): 1339-1346 Meng F; et al. (2005) Am J Physiol Cell Physiol May 25 Jin ZH; et al. (2005)Oncogene Mar 17; 24(12): 1973-1981
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around phosphorylation site of threonine 180 (E-M-T(p)-G-Y ) derived from Human P38MAPK.
- Isotyp:
- Rabbit IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:1.jpg
