Polyclonal Antibody to SP1 (Phospho-Thr739)
Produktgrößen
50 µl
£511,00
35-1224-50UL
100 µl
£581,00
35-1224-100UL
Über dieses Produkt
- SKU:
- 35-1224
- Zusätzliche Namen:
- TSFP1|| Sp1 transcription factor
- Klonalität:
- Polyclonal
- Weitere Details:
- Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth; apoptosis; differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations; sumoylation; proteolytic cleavage; glycosylation and acetylation). Binds also the PDGFR-a G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around phosphorylation site of threonine 739 (T-A-T(p)-P-S) derived from human SP1
- Isotyp:
- Rabbit IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:1.jpg