Polyclonal Antibody to FAK (Phospho-Tyr397)
Produktgrößen
50 µl
£511,00
35-1201-50UL
100 µl
£581,00
35-1201-100UL
Über dieses Produkt
- SKU:
- 35-1201
- Zusätzliche Namen:
- FAK|| FAK1|| PTK2
- Klonalität:
- Polyclonal
- Weitere Details:
- Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility; proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking; or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid; or via LDL receptor occupancy. Microtubule-induced dephosphorylation at Tyr-397 is crucial for the induction of focal adhesion disassembly. Plays a potential role in oncogenic transformations resulting in increased kinase activity.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around phosphorylation site of tyrosine 397(D-D-Y(p)-A-E)derived from Human FAK.
- Isotyp:
- Rabbit IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:1.jpg