Polyclonal Antibody to PAK1/PAK2/PAK3 (Phospho-Thr423/Thr402/Thr421)
Produktgrößen
50 µl
£511,00
35-1158-50UL
100 µl
£581,00
35-1158-100UL
Über dieses Produkt
- SKU:
- 35-1158
- Zusätzliche Namen:
- p21-activated kinase 1|| PAK-1|| p65-PAK|| Alpha-PAK
- Klonalität:
- Polyclonal
- Weitere Details:
- The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis; potentially due to binding of CDC2L1 and CDC2L2. Parsons M; et al. (2005) Mol Cell Biol ; 25:1680-1695. Jung JH; et al. (2005) J Biol Chem; 280:40025-40031. Lampugnani MG; et al. (2002) Mol Biol Cell ; 13: 1175-1189 Wang RA; et al. (2002) EMBO J; 21: 5437 - 5447.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around phosphorylation site of threonine 423 /402/421 (R-S-T(p)-M-V) derived from Human PAK1/PAK2/PAK3.
- Isotyp:
- Rabbit IgG
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:1.jpg
